| Bioactivity | Antibacterial agent 92 (Compound 36k) is a triple-site aminoacyl-tRNA synthetase (aaRS) inhibitor with an IC50 of 0.58 μM against Salmonella enterica threonyl-tRNA synthetase (SeThrRS). Antibacterial agent 92 exhibits antibacterial activities[1]. |
| Target | IC50: 0.58 μM (SeThrRS) |
| Invitro | Antibacterial agent 92 (Compound 36k) binds to the ATP site of SeThrRS[1]. |
| Name | Antibacterial agent 92 |
| Formula | C30H28Cl2F3N5O4 |
| Molar Mass | 650.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cai Z, et al. Design, Synthesis, and Proof-of-Concept of Triple-Site Inhibitors against Aminoacyl-tRNA Synthetases. J Med Chem. 2022 Apr 14;65(7):5800-5820. |
Antibacterial agent 92
CAS: F: C30H28Cl2F3N5O4 W: 650.48
Antibacterial agent 92 (Compound 36k) is a triple-site aminoacyl-tRNA synthetase (aaRS) inhibitor with an IC50 of 0.58
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