| Bioactivity | Antibacterial agent 261 (compound 43) is a potent inhibitor of peptidomimetic peptide deformylase (PDF), with IC50 of 2.5 and 10.6 nM for S. aureus and E. coli, respectively[1]. |
| CAS | 3036109-97-1 |
| Formula | C18H24N4O3S2 |
| Molar Mass | 408.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shouning Yang, et al. Design, Synthesis, and Biological Evaluation of 1,3,4-Thiadiazole Derivatives as Novel Potent Peptide Deformylase Inhibitors for Combating Drug-Resistant Gram-Positive and -Negative Bacteria. J Med Chem. 2025 Jan 7. doi: 10.1021/acs.jmedchem.4c02177 |
Antibacterial agent 261
CAS: 3036109-97-1 F: C18H24N4O3S2 W: 408.54
Antibacterial agent 261 (compound 43) is a potent inhibitor of peptidomimetic peptide deformylase (PDF), with IC50 of 2.
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