Bioactivity | Antibacterial agent 258 (Compound 11e) is an antibacterial agent, that destory the bacteria cell membrane, and inhibits various gram-positive bacteria (MIC for Staphylococcus aureus is 1-2 μg/mL). Antibacterial agent 258 exhibits low hemolytic activity and low cytotoxicity. Antibacterial agent 258 exhibits anti-infectious efficacy in mouse models[1]. |
CAS | 3054254-13-3 |
Formula | C33H50N2O |
Molar Mass | 490.76 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Huo H, et al., Design, synthesis, and biological evaluation of steroidal indole derivatives as membrane-targeting antibacterial candidates. Eur J Med Chem. 2025 Feb 5;283:117156. |