Bioactivity | Antibacterial agent 242 is a potent 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) inhibitor against Toxoplasma gondii with an IC50 value of 5.46 μM. Antibacterial agent 242 inhibits the activity of TgDXR enzyme and the proliferation of T. gondii in vitro[1]. |
Formula | C32H34ClNO6 |
Molar Mass | 564.07 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mazzone F, et al. 1-Deoxy-d-xylulose 5-phosphate reductoisomerase as target for anti Toxoplasma gondii agents: crystal structure, biochemical characterization and biological evaluation of inhibitors. Biochem J. 2024 Aug 21;481(16):1075-1096. |