Antibacterial agent 229_product_DataBase

Bioactivity	Antibacterial agent 229 (compound 8a) is a potent antibacterial agent. Antibacterial agent 229 shows antibacterial and antifungal abilities. Antibacterial agent 229 disrupts the integrity of the bacterial membrane, intercalates into DNA. Antibacterial agent 229 inhibits topoisomerase IV with an IC50 value of 10.88 µM[1].
Invitro	Antibacterial agent 229 (compound 8a) 表现出抗细菌和抗真菌能力，对 S. aureus ATCC 25923、S. aureus ATCC 29213、E. coli ATCC 25922、P. aeruginosa ATCC 27853、C. albicans ATCC 9002、C. albicans 和 C. parapsilosis ATCC 22019 的 MIC 值分别为 0.0377、0.0047、0.0189、0.0189、0.0189、0.0047 mM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antibacterial agent 229 相关抗体:
Formula	C16H14ClFN6OS2
Molar Mass	424.90
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Zang ZL, et al. Synthesis and antibacterial medicinal evaluation of carbothioamido hydrazonyl thiazolylquinolone with multitargeting antimicrobial potential to combat increasingly global resistance. Eur J Med Chem. 2024 Sep 5;275:116626.

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