| Bioactivity | Antibacterial agent 228 (Compound 8) inhibits the mycobacterial ribosome (IC50 for Mycobacterium smegmatis is 2.31 μM) and exhibits antibacterial activity against M. tuberculosis H37Rv (MIC=2 and 0.25 μg/mL for wildtype and Δ1258c mutant), M. abscessus ATCC 19977 (MIC=8 and 8 μg/mL for wildtype and Δ2780c mutant) and M. smegmatis (MIC=8 μg/mL)[1]. |
| Formula | C26H42FN3O7 |
| Molar Mass | 527.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dharuman S, et al., Synthesis and antibacterial action of 3',6'-disubstituted spectinomycins. J Antibiot (Tokyo). 2024 Jun 18. |
Antibacterial agent 228
CAS: F: C26H42FN3O7 W: 527.63
Antibacterial agent 228 (Compound 8) inhibits the mycobacterial ribosome (IC50 for Mycobacterium smegmatis is 2.31 μM)
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