Antibacterial agent 227_product_DataBase

Bioactivity	Antibacterial agent 227 (Compd 29) is a SerRS (Seryl-tRNA synthetase) inhibitor. Antibacterial agent 227 has a significant inhibitory effect on the growth of planktonic and biofilm culture of Staphylococcus aureus 25923 with MIC (minimum inhibitory concentration) value of 32 µg/ml. Antibacterial agent 227 can be proposed as effective antiseptic toward multidrug-resistant biofilm-forming S. aureus isolates[1].
Target	Seryl-tRNA synthetase (SerRS)
Invitro	Antibacterial agent 227 (0-32 µg/ml) 对 S. aureus 25923 的浮游培养物具有显著的抑制作用，但对革兰氏阴性菌 E. coli 并未显示抗菌活性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antibacterial agent 227 相关抗体:
CAS	301304-67-6
Formula	C12H13N5O3
Molar Mass	275.26
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Volynets GP, et al. Identification of novel antistaphylococcal hit compounds. J Antibiot (Tokyo). 2024 Jun 25.

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