| Bioactivity | Antibacterial agent 224 is a potent and selective synthetic hydrazone inhibitor against the Salmonella PhoP/PhoQ system[1]. |
| Invitro | Antibacterial agent 224 (compound A16B1) 抑制沙门氏菌 PhoP/PhoQ 系统活性，特别是针对第二跨膜区域内的 PhoQ。Antibacterial agent 224 (compound A16B1) 与抗菌肽粘菌素具有协同作用，可减少沙门氏菌的巨噬细胞内增殖，而不会产生细胞毒性，并提高全身感染沙门氏菌的 G. mellonella 幼虫的存活率[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antibacterial agent 224 相关抗体: |
| Formula | C12H10N2OS |
| Molar Mass | 230.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Carlos A Lobertti, et al. An allosteric inhibitor of the PhoQ histidine kinase with therapeutic potential against Salmonella infection. J Antimicrob Chemother. 2024 Jun 10:dkae151. |
Antibacterial agent 224
CAS: F: C12H10N2OS W: 230.29
Antibacterial agent 224 is a potent and selective synthetic hydrazone inhibitor against the Salmonella PhoP/PhoQ system.
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This product is for research use only, not for human use. We do not sell to patients.