Bioactivity | Antibacterial agent 190 (compound 16) is a antibacterial agent. Antibacterial agent 190 shows antibacterial activity. Antibacterial agent 190 reduces the bacterial burden of the peritoneum and blood[1]. |
Invitro | Antibacterial agent 190 显示出对 Streptococcus pneumoniae, Enterococcus faecium, Vancomycin-resistant Enterococcus faecium, Linezolid-resistant Enterococcus faecium 的抗菌活性,MIC 值为 0.12-0.25、0.03、0.12、0.03、0.12 μg/mL[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antibacterial agent 190 相关抗体: |
In Vivo | Antibacterial agent 190 (80 mg/kg; s.c.) 可降低小鼠脓毒症/腹膜炎感染模型中腹膜和血液的细菌负荷[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
Formula | C39H50N10O4 |
Molar Mass | 722.88 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Heidtmann CV, et al. Hit-to-Lead Identification and Validation of a Triaromatic Pleuromutilin Antibiotic Candidate. J Med Chem. 2024 Feb 22. |