| Bioactivity | Antiangiogenic agent 7 (Compound 1) can induce cell apoptosis, increase Reactive Oxygen Species, and inhibit the intracellular enzyme thioredoxin reductase. Antiangiogenic agent 7 has anti-cancer activity, with an IC50 of 0.08-3.5 μM against cervical cancer cells HeLa, prostate cancer cells PC-3, and non-small cell lung cancer A549. Antiangiogenic agent 7 inhibits tumor growth in mouse xenograft models[1]. |
| CAS | 2527888-07-7 |
| Formula | C24H26AuN3P2S |
| Molar Mass | 647.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. T. Srinivasa Reddy, et al. Gold(I) complexes of the type [AuL{κC-2-C6H4P(S)Ph2}] [L = PTA, PPh3, PPh2(C6H4-3-SO3Na) and PPh2(2-py)]: Synthesis, characterisation, crystal structures, and In Vitro and In Vivo anticancer properties. European Journal of Medicinal Chemistry. Volume 281, 5 January 2025, 117007. |
Antiangiogenic agent 7
CAS: 2527888-07-7 F: C24H26AuN3P2S W: 647.46
Antiangiogenic agent 7(Compound 1) can induce cell apoptosis, increase Reactive Oxygen Species, and inhibit the intracel
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