| Bioactivity | Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV)[1][2]. | ||||||||||||
| Invitro | Anti-virus agent 1 (compound 4i) has antiviral activity for EBOV in HeLa cell (EC50=1845 nM), HMVEC cell (TERT-immortalized human foreskin microvascular endothelial cells; ATCC-4025; EC50=367 nM), human macrophages (EC50=297 nM). Anti-virus agent 1 has a CC50 of 21 μM in MT4 cell (human leukemia T-cell)[1]. | ||||||||||||
| Name | Anti-virus agent 1 | ||||||||||||
| CAS | 1911578-83-0 | ||||||||||||
| Formula | C24H29N6O8P | ||||||||||||
| Molar Mass | 560.50 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Anti-virus agent 1
CAS: 1911578-83-0 F: C24H29N6O8P W: 560.50
Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734 (HY-104077; Remdesivir), has potent antiviral act
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