Anti-melanoma agent 3_product_DataBase

Bioactivity	Anti-melanoma agent 3 (compound 5cb) is a 2-aryl-4-benzoyl-imidazole (ABI) derivative and an inhibitor of melanoma xenogeneic tumors. Anti-melanoma agent 3 exerts anticancer activity by interacting with the colchicine binding site to inhibit tubulin polymerization[1].
Invitro	Anti-melanoma agent 3 具有抗增殖活性，可抑制黑色素瘤细胞系和前列腺癌细胞系生长[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Anti-melanoma agent 3 相关抗体:
In Vivo	Anti-melanoma agent 3 (10, 30 mg/kg; ip; 每天 1 次, 共 14 天) 可显著抑制 B16-F1 荷瘤小鼠的肿瘤生长[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS	1253697-49-2
Formula	C17H13FN2O2
Molar Mass	296.30
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Chen J, et al. Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents. J Med Chem. 2010 Oct 28;53(20):7414-27.

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