Anti-inflammatory agent 78_product_DataBase

Bioactivity	Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. Anti-inflammatory agent 78 has significant potency on PGE2, PGE1, COX-2 and COX-1 inhibition. Anti-inflammatory agent 78 can inhibits NO release in LPS-stimulated RAW 264.7 cell line[1].
Invitro	Anti-inflammatory agent 78 (compound L-37) 在10 μM时具有较高的肿瘤细胞生长抑制能力，对RAW 264.7细胞的生长有显着影响[1]。Anti-inflammatory agent 78 (1-10 μM，24 h) 可抑制 RAW 264.7 细胞中 LPS 诱导的 PGE2 合成[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Anti-inflammatory agent 78 相关抗体: Cell Viability Assay[1] Cell Line:
In Vivo	Anti-inflammatory agent 78 (compound L-37) (25-100 mg/kg, 腹腔注射) 在二甲苯诱导的小鼠耳水肿模型中表现出显着的体内抗炎活性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
Formula	C19H14ClNO4
Molar Mass	355.77
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Akhtar M, et al. A series of indole-derived γ-hydroxy propiolate esters as potent anti-inflammatory agents: Design, synthesis, in-vitro and in-vivo biological studies. Eur J Med Chem. 2024 Apr 15;270:116376.

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