| Bioactivity | Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway[1]. |
| Invitro | Anti-inflammatory agent 41 (13a) 显著减少了LPS诱导的p65在J774A.1巨噬细胞中的核转位。 |
| Name | Anti-inflammatory agent 41 |
| CAS | 2896204-90-1 |
| Formula | C33H25N3O5 |
| Molar Mass | 543.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jun Yang, et al. Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis. Eur J Med Chem. 2023 Mar 5;249:115144. |
Anti-inflammatory agent 41
CAS: 2896204-90-1 F: C33H25N3O5 W: 543.57
Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammator
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.