| Bioactivity | Anti-inflammatory agent 21 (compound 9o) is an orally active and low cytotoxic anti-inflammatory agent, with an IC50 value of 0.76 μM for NO. Anti-inflammatory agent 21 acts via accumulation ROS and blocks the NF-κB/MAPK signaling pathway. Anti-inflammatory agent 21 can ameliorate cartilage destruction and inflammatory cell infiltration in arthritis rats model[1]. |
| Target | IC50: 0.76 μM (NO) |
| Name | Anti-inflammatory agent 21 |
| CAS | 2408836-40-6 |
| Formula | C24H21FO6 |
| Molar Mass | 424.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen LZ, Wu J, Li K, et al. Novel phthalide derivatives: Synthesis and anti-inflammatory activity in vitro and in vivo. Eur J Med Chem. 2020;206:112722. |
Anti-inflammatory agent 21
CAS: 2408836-40-6 F: C24H21FO6 W: 424.42
Anti-inflammatory agent 21 (compound 9o) is an orally active and low cytotoxic anti-inflammatory agent, with an IC50 val
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