PeptideDB

Anti-Influenza agent 4

CAS: 522625-85-0 F: C19H18N2O5S W: 386.42

Anti-Influenza agent 4 is a potent and selective influenza virus inhibitor with EC50s of 150 nM and 62 nM for strains A/
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Bioactivity Anti-Influenza agent 4 is a potent and selective influenza virus inhibitor with EC50s of 150 nM and 62 nM for strains A/Roma and A/Parma, respectively[1].
Target EC50: 150±0.07 nM (A/Roma), 62±0.02 nM (A/Parma)
Invitro Anti-Influenza agent 4 (compound 5) (0-500 μM; 24 and 48 h) exhibits low cytotoxicity in MDCK cells[1].Anti-Influenza agent 4 shows highly antiviral activity against influenza strain A/Roma and A/Parma with EC50s of 150±0.07 nM and 62±0.02 nM, respectively[1].Anti-Influenza agent 4 shows IC50s of 244 nM and 230.7 nM against influenza strain A/Roma and A/Parma in hemolysis inhibition assay[1]. Cell Cytotoxicity Assay[1] Cell Line:
Name Anti-Influenza agent 4
CAS 522625-85-0
Formula C19H18N2O5S
Molar Mass 386.42
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Agamennone M, Pietrantoni A, Superti F. Identification of small molecules acting against H1N1 influenza A virus. Virology. 2016 Jan 15;488:249-58.