| Bioactivity | Anti-Influenza agent 4 is a potent and selective influenza virus inhibitor with EC50s of 150 nM and 62 nM for strains A/Roma and A/Parma, respectively[1]. |
| Target | EC50: 150±0.07 nM (A/Roma), 62±0.02 nM (A/Parma) |
| Invitro | Anti-Influenza agent 4 (compound 5) (0-500 μM; 24 and 48 h) exhibits low cytotoxicity in MDCK cells[1].Anti-Influenza agent 4 shows highly antiviral activity against influenza strain A/Roma and A/Parma with EC50s of 150±0.07 nM and 62±0.02 nM, respectively[1].Anti-Influenza agent 4 shows IC50s of 244 nM and 230.7 nM against influenza strain A/Roma and A/Parma in hemolysis inhibition assay[1]. Cell Cytotoxicity Assay[1] Cell Line: |
| Name | Anti-Influenza agent 4 |
| CAS | 522625-85-0 |
| Formula | C19H18N2O5S |
| Molar Mass | 386.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Agamennone M, Pietrantoni A, Superti F. Identification of small molecules acting against H1N1 influenza A virus. Virology. 2016 Jan 15;488:249-58. |