Anti-Influenza agent 3_product_DataBase

Bioactivity	Anti-Influenza agent 3 (compound 11h) is a potent anti-influenza agent with EC50 values of 3.29, 2.45 µM for A/HK/68 (H3N2, M2-WT), A/WSN/33 (H1N1, M2-S31N) strain, respectively. Anti-Influenza agent 3 shows low cytotoxicity for MDCK epithelial cells. Anti-Influenza agent 3 inhibits the M2 WT and S31N ion channel conductivity[1].
Target	EC50: 3.29 µM (H3N2); 2.45 µM (H1N1).
Invitro	Anti-Influenza agent 3 shows lowe cytotoxicity for MDCK epithelial cells with an TC50 of >173.14 µM[1].Anti-Influenza agent 3 (100 µM) inhibits the M2 WT and S31N ion channel conductivity in 293 T-Rex cells[1].
Name	Anti-Influenza agent 3
Formula	C16H22ClNOS
Molar Mass	311.87
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Dong J, Xiao M, Ma Q, Zhang G, Zhao W, Kong M, Zhang Y, Qiu L, Hu W. Design and synthesis of pinane oxime derivatives as novel anti-influenza agents. Bioorg Chem. 2020 Sep;102:104106.

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