Anthopleurin-A_product_DataBase

Bioactivity	Anthopleurin-A is a soidum channel toxin. Anthopleurin-A is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A can be isolated from the sea anemone[1][2].
Invitro	Anthopleurin-A (2 nM-640 nM) 可增强离体猫心脏乳头肌的收缩力[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Anthopleurin-A 相关抗体:
In Vivo	Anthopleurin-A (0.2 μg/kg/min，静脉注射) 可增加麻醉犬的心肌收缩力[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS	60880-63-9
Sequence	Gly-Val-Ser-Cys-Leu-Cys-Asp-Ser-Asp-Gly-Pro-Ser-Val-Arg-Gly-Asn-Thr-Leu-Ser-Gly-Thr-Leu-Trp-Leu-Tyr-Pro-Ser-Gly-Cys-Pro-Ser-Gly-Trp-His-Asn-Cys-Lys-Ala-His-Gly-Pro-Thr-Ile-Gly-Trp-Cys-Cys-Lys-Gln (Disulfide bridge: Cys4-Cys46,Cys6-Cys36,Cys29- Cys47)
Shortening	GVSCLCDSDGPSVRGNTLSGTLWLYPSGCPSGWHNCKAHGPTIGWCCKE (Disulfide bridge: Cys4-Cys46,Cys6-Cys36,Cys29- Cys47)
Formula	C220H326N64O67S6
Molar Mass	5131.72
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Honma T, Shiomi K. Peptide toxins in sea anemones: structural and functional aspects. Mar Biotechnol (NY). 2006 Jan-Feb;8(1):1-10. [2]. Scriabine A, et al. Cardiotonic effects of anthopleurin-A, a polypeptide from a sea anemone. J Cardiovasc Pharmacol. 1979 Sep-Oct;1(5):571-83.

PeptideDB