| Bioactivity | Anitrazafen is a topically effective antiinflammatory agent. |
| In Vivo | Anitrazafen is a topically effective antiinflammatory agent. The disposition of 14C in normal and in bile-duct cannulated rats after oral administration of a single dose of 25 mg/kg of [3-14C]Anitrazafen shows the drug to be well absorbed from the gastro-intestinal tract and biliary excretion to be the major route of elimination of drug and/or metabolites. Plasma concentrations of total 14C after subcutaneous administration of [3-14C]Anitrazafen in corn oil solution are about one half those found after oral administration[1]. |
| Name | Anitrazafen |
| CAS | 63119-27-7 |
| Formula | C18H17N3O2 |
| Molar Mass | 307.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sullivan HR, et al. Absorption and metabolism of anitrazafen, a topically effective anti-inflammatory agent, in the rat. Xenobiotica. 1981 Jan;11(1):9-22. |