Bioactivity | Angiotensin II type 1 receptor (181-187) is a 9-amino acid sequence of the second extracellular loop of angiotensin II (Ang II) in the renin-angiotensin system. Angiotensin II type 1 receptor (181-187) serves as the localization epitope of angiotensin II receptor autoantibodies (AT1RaAb) and is used to detect and quantify AT1RaAb levels in serum[1]. |
CAS | 275359-37-0 |
Sequence | Ala-Phe-His-Tyr-Glu-Ser-Gln |
Shortening | AFHYESQ |
Formula | C40H52N10O13 |
Molar Mass | 880.90 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Abadir, et al. "Discovery and validation of agonistic angiotensin receptor autoantibodies as biomarkers of adverse outcomes." Circulation 135.5 (2017): 449-459. |