| Bioactivity | Angiotensin II (5-8), human is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II[1]. Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney[2][3]. | ||||||
| Name | Angiotensin II (5-8), human | ||||||
| CAS | 34233-50-6 | ||||||
| Sequence | Ile-His-Pro-Phe | ||||||
| Shortening | IHPF | ||||||
| Formula | C26H36N6O5 | ||||||
| Molar Mass | 512.60 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |