| Bioactivity | Anagyrine ((-)-Anagyrine) is a quinolizidine alkaloid that has been found in Lupinus albus. Anagyrine binds to muscarinic and nicotinic acetylcholine receptors with IC50 values of 132 and 2096 µM respectively. Anagyrine is a potent and effective desensitizer of nAChR, and Anagyrine can directly, without metabolism, desensitize nAChR[1][2][3]. |
| Invitro | Anagyrine 在 SH-SY5Y 和 TE-671 两种细胞系中均充当部分激动剂， EC50 值分别为 4.2 和 231 μM。 Anagyrine 是 nAChR 的脱敏剂，在 SH-SY5Y 和 TE-671 细胞中的 DC50 值分别为 6.9 和 139 μM[3]。 |
| Name | Anagyrine |
| CAS | 486-89-5 |
| Formula | C15H20N2O |
| Molar Mass | 244.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |