| Bioactivity | Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth[1][2][3]. |
| Invitro | Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) (1-100 µM; 24 hours; L. acidophilus) decreases living cells and increases degree of cell wall rupture in a dose-dependent manner[1]. |
| In Vivo | Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) (7 mg/kg; i.h.; female ICR/Swiss mice) inhibits strain numbers and improves the survival rate of rats in 1 mg/L or less[2].Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) (1.6-9.5 mg/kg; p.o.; daily, for 7 or 14 days; swiss albino mice) has against infection with chlamydia trachomatis in mice[3]. Animal Model: |
| Name | Amoxicillin trihydrate mixture with potassium clavulanate (4:1) |
| Formula | C24H33KN4O13S |
| Molar Mass | 656.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Guo Y, et, al. Metabolic response of Lactobacillus acidophilus exposed to amoxicillin. J Antibiot (Tokyo). 2022 May;75(5):268-281. [2]. Andes D, et, al. In vivo activities of amoxicillin and amoxicillin-clavulanate against Streptococcus pneumoniae: application to breakpoint determinations. Antimicrob Agents Chemother. 1998 Sep;42(9):2375-9. [3]. Kramer MJ, et, al. Activity of oral amoxicillin, ampicillin, and oxytetracycline against infection with chlamydia trachomatis in mice. J Infect Dis. 1979 Jun;139(6):717-9. [4]. Michael Spector, et al. Formulations of amoxicillin and clavulanate potassium and methods for using same. WO2013173803A2. |
Amoxicillin trihydrate mixture with potassium clavulanate (4:1)
CAS: F: C24H33KN4O13S W: 656.70
Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) an antibiotic with good oral absorption and broad spec
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