| Bioactivity | Amorfrutin A is the inhibition of NF-κB activation, that inhibits TNF-α-induced IκBα degradation, p65 nuclear translocation, and DNA-binding activity. Amorfrutin A promotes TNF-α-induced apoptosis in HeLa cell through promotion of caspase-3 and PARP proteolysis[1]. |
| CAS | 80489-90-3 |
| Formula | C21H24O4 |
| Molar Mass | 340.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shi H, et al., Amorfrutin A inhibits TNF-α-induced NF-κB activation and NF-κB-regulated target gene products. Int Immunopharmacol. 2014 Jul;21(1):56-62. |