| Bioactivity | Amitriptyline (hydrochloride) (Standard) is the analytical standard of Amitriptyline (hydrochloride). This product is intended for research and analytical applications. Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity. |
| Name | Amitriptyline hydrochloride (Standard) |
| CAS | 549-18-8 |
| Formula | C₂₀H₂₄ClN |
| Molar Mass | 313.86 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Amitriptyline hydrochloride (Standard)
CAS: 549-18-8 F: C₂₀H₂₄ClN W: 313.86
Amitriptyline (hydrochloride) (Standard) is the analytical standard of Amitriptyline (hydrochloride). This product is in
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This product is for research use only, not for human use. We do not sell to patients.