| Bioactivity | Amiprofos methyl (BAY-NTN 6867) is a phosphoric amide herbicide. Amiprofos methyl is a specific and potent antimicrotubule agent. Amiprofos methyl directly poisons microtubule dynamics in plant cells[1]. | |||||||||
| Invitro | Amiprofos methyl (APM) inhibits competitively the binding of [14C]oryzalin to tubulin with a Ki=5 μM. Amiprofos methyl concentrations inhibiting tobacco cell growth were within the threshold range of Amiprofos methyl concentrations that depolymerized cellular microtubules, indicating that growth inhibition is caused by microtubules depolymerization[2]. | |||||||||
| Name | Amiprofos methyl | |||||||||
| CAS | 36001-88-4 | |||||||||
| Formula | C11H17N2O4PS | |||||||||
| Molar Mass | 304.30 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Morejohn LC, et al. Inhibition of Plant Microtubule Polymerization in vitro by the Phosphoric Amide Herbicide Amiprophos-Methyl. Science. 1984;224(4651):874-876. [2]. Murthy JV, et al. Competitive Inhibition of High-Affinity Oryzalin Binding to Plant Tubulin by the Phosphoric Amide Herbicide Amiprophos-Methyl. Plant Physiol. 1994;105(1):309-320. |
Amiprofos methyl
CAS: 36001-88-4 F: C11H17N2O4PS W: 304.30
Amiprofos methyl (BAY-NTN 6867) is a phosphoric amide herbicide. Amiprofos methyl is a specific and potent antimicrotubu
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