| Bioactivity | Aminopurvalanol A is a potent, selective, and cell permeable inhibitor of Cyclins/Cdk complexes. Aminopurvalanol A preferentially targets the G2/M-phase transition inhibiting cancer cell differentiation. Aminopurvalanol A causes the inhibition of sperm fertilizing ability via the inhibition of physiological capacitation-dependent actin polymerization[1][2]. | ||||||||||||
| Invitro | Aminopurvalanol A (5 and 40 μM; 8 hours) inhibits cell growth primarily by arresting the cells in the G2 phase of the cell cycle and, at higher concentration, triggering apoptosis[2]. Cell Cycle Analysis[2] Cell Line: | ||||||||||||
| Name | Aminopurvalanol A | ||||||||||||
| CAS | 220792-57-4 | ||||||||||||
| Formula | C19H26ClN7O | ||||||||||||
| Molar Mass | 403.91 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Aminopurvalanol A
CAS: 220792-57-4 F: C19H26ClN7O W: 403.91
Aminopurvalanol A is a potent, selective, and cell permeable inhibitor of Cyclins/Cdk complexes. Aminopurvalanol A prefe
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