| Bioactivity | Aminopterin N-hydroxysuccinimide ester(NHS-methotrexate) is an irreversible Methotrexate (HY-14519) influx carrier inhibitor. Aminopterin N-hydroxysuccinimide ester can be used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia)[1][2]. |
| CAS | 98457-88-6 |
| Formula | C24H27N9O8 |
| Molar Mass | 569.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Henderson GB, et al. Characterization of the multiple transport routes for methotrexate in L1210 cells using phthalate as a model anion substrate. J Membr Biol. 1985;85(3):263-268. [2]. Chiao JH, et al. RFC-1 gene expression regulates folate absorption in mouse small intestine. J Biol Chem. 1997;272(17):11165-11170. |
Aminopterin N-hydroxysuccinimide ester
CAS: 98457-88-6 F: C24H27N9O8 W: 569.53
Aminopterin N-hydroxysuccinimide ester(NHS-methotrexate) is an irreversible Methotrexate (HY-14519) influx carrier inhib
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