| Bioactivity | Aminoacyl tRNA synthetase-IN-3 (compound 36K3) is an inhibitor of lysine tRNA synthetase (PfLysRS) from Plasmodium falciparum (IC50=59.2 nM), which inhibits the activity of PfLysRS by occupying the ATP binding site and L-lysine binding site of PfLysRS. Aminoacyl tRNA synthetase-IN-3 can be used in the development of antimalarial drugs[1]. |
| Formula | C26H36N8O5S |
| Molar Mass | 572.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhou J, et al. Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors[J]. Communications Biology, 2024, 7(1): 742. |
Aminoacyl tRNA synthetase-IN-3
CAS: F: C26H36N8O5S W: 572.68
Aminoacyl tRNA synthetase-IN-3 (compound 36K3) is an inhibitor of lysine tRNA synthetase (PfLysRS) from Plasmodium falci
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.