| Bioactivity | Amb123203 is an antiviral compound with the activity of inhibiting viral budding. Amb123203 exerts its effect by blocking the interaction between mVP40 and Nedd4 proteins. Amb123203 has a significant inhibitory effect on the budding of VP40 virus-like particles (VLPs) of Marburg (MARV) and Ebola viruses. Amb123203 can effectively target RNA viruses that rely on the PPxY L domain for efficient budding, showing broad-spectrum antiviral activity. The discovery of Amb123203 provides an important basis for the development of new broad-spectrum antiviral compounds[1]. |
| CAS | 956571-77-0 |
| Formula | C25H27N5OS |
| Molar Mass | 445.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Small-molecule probes targeting the viral PPxY-host Nedd4 interface block egress of a broad range of RNA viruses |
Amb123203
CAS: 956571-77-0 F: C25H27N5OS W: 445.58
Amb123203 is an antiviral compound with the activity of inhibiting viral budding. Amb123203 exerts its effect by blockin
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