| Bioactivity | Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs=25, 25, and 3.1 μg/mL, respectively).2 Althiomycin inhibits protein synthesis in E. coli when used at concentrations of 1 and 10 μg/mL but not in isolated rabbit reticulocytes at 100 μg/mL. |
| CAS | 12656-40-5 |
| Formula | C16H17N5O6S2 |
| Molar Mass | 439.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gerc, et al. The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin. PLoS One 7(9), e44673 (2012). |
Althiomycin
CAS: 12656-40-5 F: C16H17N5O6S2 W: 439.47
Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active a
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