| Bioactivity | Aldose reductase-IN-6 (Compound 3) is a competitive aldose reductase (AR) inhibitor with an IC50 of 3.164 μM and a Ki of 0.018 μM. Aldose reductase-IN-6 exhibits no cytotoxicity against healthy cells[1]. |
| Target | IC50: 3.164 μM (Aldose Reductase) |
| Name | Aldose reductase-IN-6 |
| CAS | 2470019-41-9 |
| Formula | C20H16N4O2S |
| Molar Mass | 376.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sever B, et al. Design, synthesis, in vitro and in silico investigation of aldose reductase inhibitory effects of new thiazole-based compounds. Bioorg Chem. 2020 Sep;102:104110. |
Aldose reductase-IN-6
CAS: 2470019-41-9 F: C20H16N4O2S W: 376.43
Aldose reductase-IN-6 (Compound 3) is a competitive aldose reductase (AR) inhibitor with an IC50 of 3.164 μM and a Ki o
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