| Bioactivity | Aldose reductase-IN-3 (Compound 5) is a potent and moderately selective inhibitor of aldose reductase (AR) with an IC50 of 3.99 μM. Aldose reductase has recently emerged as a molecular target that is involved in various inflammatory diseases, including sepsis. Aldose reductase-IN-3 has the potential for the research of sepsis[1]. |
| Name | Aldose reductase-IN-3 |
| CAS | 1390616-76-8 |
| Formula | C18H12ClN3O2S2 |
| Molar Mass | 401.89 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kousaxidis A, et al. Non-acidic bifunctional benzothiazole-based thiazolidinones with antimicrobial and aldose reductase inhibitory activity as a promising therapeutic strategy for sepsis [published online ahead of print, 2021 Aug 4]. Med Chem Res. 2021;1 |
Aldose reductase-IN-3
CAS: 1390616-76-8 F: C18H12ClN3O2S2 W: 401.89
Aldose reductase-IN-3 (Compound 5) is a potent and moderately selective inhibitor of aldose reductase (AR) with an IC50
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