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Albendazole sulfoxide-d7

CAS: 2469575-37-7 F: C12H8D7N3O3S W: 288.37

Albendazole sulfoxide-d7 is the deuterium labeled Albendazole sulfoxide. Albendazole sulfoxide (Ricobendazole), the main
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Albendazole sulfoxide-d7 is the deuterium labeled Albendazole sulfoxide. Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1].
Invitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name Albendazole sulfoxide-d7
CAS 2469575-37-7
Formula C12H8D7N3O3S
Molar Mass 288.37
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Gokhan Adas,, et al. Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study).