| Bioactivity | Alatrioprilat is an orally active inhibitor of angiotensin-converting enzyme (ACE) (IC50=19.6 nM; Ki=9.8 nM) and enkephailnase (IC50=6.1 nM; Ki=5.1 nM). Alatrioprilat plays a key role in the metabolism of hormonal peptides through the degradation of nitric oxide and atrial natriuretic factor (ANF). Alatrioprilat can be used in the study of cardiovascular diseases[1]. |
| CAS | 135038-59-4 |
| Formula | C14H17NO5S |
| Molar Mass | 311.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gros C, et al. Mixed inhibitors of angiotensin-converting enzyme (EC 3.4. 15.1) and enkephalinase (EC 3.4. 24.11): rational design, properties, and potential cardiovascular applications of glycopril and alatriopril[J]. Proceedings of the National Academy of Sciences, 1991, 88(10): 4210-4214. |
Alatrioprilat
CAS: 135038-59-4 F: C14H17NO5S W: 311.35
Alatrioprilat is an orally active inhibitor of angiotensin-converting enzyme (ACE) (IC50=19.6 nM; Ki=9.8 nM) and enkepha
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