Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2_product_DataBase

Bioactivity	Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biological active peptide. (Protease activated receptor 1 (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. This peptide is a PAR-1 selective agonist displaying a high level of specificity to PAR-1 over PAR-2. The specificity of peptide was evaluated in cell-based calcium signaling assay using HEK293 cells. PAR-1 selective agonists can be used to study PAR-1 activation in vivo. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'.)
Name	Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
CAS	211190-38-4
Sequence	Ala-{Phe(p-Fluoro)}-Arg-{Cha}-{Cit}-Tyr-NH2
Shortening	A-{Phe(p-Fluoro)}-R-{Cha}-{Cit}-Y-NH2
Formula	C42H63FN12O8
Molar Mass	883.02
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

PeptideDB