| Bioactivity | Akt/ROCK-IN-1 (B12) is a dual inhibitor for Akt and ROCK, with the IC50s of 0.023 nM and 1.47 nM, respectively. Akt/ROCK-IN-1 has antitumor activity for neuroblastoma[1]. |
| Name | Akt/ROCK-IN-1 |
| Formula | C21H19BrF2N4O2S |
| Molar Mass | 509.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jinxin Che, et al. Discovery of Novel Oxazepine Derivatives as Akt/ROCK Inhibitors for Growth Arrest and Differentiation Induction in Neuroblastoma Treatment. J Med Chem. 2023 Oct 12;66(19):13530-13555. |