Bioactivity | Aglepristone is a synthetic steroidal antiprogestin with abortifacient activity. Aglepristone is used exclusively as an abortifacient in pregnant animals. Aglepristone has been shown to be a safe and effective abortifacient in the second trimester of pregnancy. Aglepristone causes termination of pregnancy and does not cause fetal resorption. During aglepristone treatment, an increase in plasma concentrations of prolactin was observed, while progesterone levels remained unchanged. The use of aglepristone also resulted in early arrest of corpus luteum function and a shortening of the estrus interval[1]. |
CAS | 124478-60-0 |
Formula | C29H37NO2 |
Molar Mass | 431.61 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Termination of mid-gestation pregnancy in bitches with aglepristone, a progesterone receptor antagonist |