| Bioactivity | Afegostat TFA is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity[1]. |
| CAS | 1084896-50-3 |
| Formula | C8H14F3NO5 |
| Molar Mass | 261.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Richter F, et al. A GCase chaperone improves motor function in a mouse model of synucleinopathy. Neurotherapeutics. 2014 Oct;11(4):840-56. |
Afegostat TFA
CAS: 1084896-50-3 F: C8H14F3NO5 W: 261.20
Afegostat TFA is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the
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