Aerothionin_product_DataBase

Bioactivity	Aerothionin is an antibiotic with potent antimicrobial efficacy against bacteria and fungi. Aerothionin exhibits antitumor efficacy against adrenal pheochromocytomas and extra-adrenal paragangliomas (PPGLs)[1][2].
Invitro	Aerothionin (0-100 μM, 24h) 抑制嗜铬细胞瘤细胞 MPC 和 MTT 的增殖，抑制 MTT 细胞球体生长 (10 μM) [1]。Aerothionin (0-100 μM, 24h) 对正常内皮细胞 HUVECs 表现出毒性，轻微刺激正常成纤维细胞 3T3[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Aerothionin 相关抗体: Cell Viability Assay[1] Cell Line:
CAS	28714-26-3
Formula	C24H26Br4N4O8
Molar Mass	818.10
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Drechsel A, et al., Anti-Tumor Activity vs. Normal Cell Toxicity: Therapeutic Potential of the Bromotyrosines Aerothionin and Homoaerothionin In Vitro. Mar Drugs. 2020 May 1;18(5):236. [2]. Šimovičová M. Synthesis of aerothionin analogs as potential antimycobacterial agents[J]. 2021.

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