| Bioactivity | Adrenorphin is a opioid octapeptide, acting as a potent agonist of μ-opioid receptor, with Ki of 12 nM. | ||||||
| Invitro | Adrenorphin (Metorphamide) is a opioid octapeptide from bovine brain, acts as a potent agonist of μ-opioid receptor, with Ki of 12 nM. The binding ratios of Ki for μ-opioid receptor/Ki for δ-opioid receptor of 0.04 and of Ki for μ-opioid receptor/Ki for κ-opioid receptor of 0.46[1]. Adrenorphin potently inhibits catecholamine secretion evoked by 10 μM nicotine in cultured human pheochromocytoma 6 cells, with an IC50 of 1.1 μM[2]. | ||||||
| Name | Adrenorphin | ||||||
| CAS | 88377-68-8 | ||||||
| Sequence | Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2 | ||||||
| Shortening | YGGFMRRV-NH2 | ||||||
| Formula | C44H69N15O9S | ||||||
| Molar Mass | 984.18 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |