| Bioactivity | Actinopyrone A is a pyrone isolated from S. pactum with diverse biological activities. It has selective and potent antimicrobial activity against H. pylori (MIC=0.1 ng/mL) with no activity against other Gram-negative bacteria including E. coli, K. pneumoniae, P. aeruginosa, and B. fragilis. Actinopyrone A also mildly inhibits growth of Gram-positive bacteria and dermatophytes with MIC values ranging from 1 Intravenous administration of actinopyrone A (30 μg/kg) increases coronary blood flow in dogs by 196.2%. |
| CAS | 88378-59-0 |
| Formula | C25H36O4 |
| Molar Mass | 400.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yano, et al. Actinopyrones A, B and C, new physiologically active substances. I. Producing organism, fermentation, isolation and biological properties. J. Antibiot. (Tokyo) 39(1), 32-37 (1986). |