Bioactivity | Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM[1]. |
Name | Acridone-4-carboxylic acid |
CAS | 24782-64-7 |
Formula | C14H9NO3 |
Molar Mass | 239.23 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Pal C, et al. Synthesis of novel heme-interacting acridone derivatives to prevent free heme-mediated protein oxidation and degradation. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3563-7. |