Acetyl-CoA Carboxylase-IN-1_product_DataBase

CAS: 179343-23-8 F: C13H9Br2N5 W: 395.05

Acetyl-CoA Carboxylase-IN-1 is a potent acetyl-CoA carboxylase (ACC) inhibitor with an IC50 value of ＜5 nM. Acetyl-CoA

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

Acetyl-CoA Carboxylase-IN-1 is a potent acetyl-CoA carboxylase (ACC) inhibitor with an IC50 value of ＜5 nM. Acetyl-CoA Carboxylase-IN-1 has antibacterial activity[1].

Invitro

Acetyl-CoA Carboxylase-IN-1 (compound 1; 0.012-25 μM; 大肠杆菌) 具有抗菌活性，对于 WT、WT+ PMBN、ΔacrAB、ΔacrAB+PMBN、ΔtolC 和 ΔtolC+ PMBN 的 MIC 值分别为 >25、3.13、25、0.39、1.56 和 0.1 μM[1]。

Name

Acetyl-CoA Carboxylase-IN-1

CAS

179343-23-8

Formula

C13H9Br2N5

Molar Mass

395.05

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Cifone MT, et, al. Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity. J Med Chem. 2022 Dec 22;65(24):16510-16525.

PeptideDB

Acetyl-CoA Carboxylase-IN-1

CAS: 179343-23-8 F: C13H9Br2N5 W: 395.05