| Bioactivity | Acetyl-Calpastatin(184-210)(human) is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin L, respectively[1][2]. | ||||||
| Invitro | Acetyl-Calpastatin(184-210)(human) (peptide 1; 12.5-100 μM) inhibits calpains in LCLC 103H cells with an IC50 of 27 μM[1]. | ||||||
| Name | Acetyl-Calpastatin(184-210)(human) | ||||||
| CAS | 123714-50-1 | ||||||
| Sequence | Ac-Asp-Pro-Met-Ser-Ser-Thr-Tyr-Ile-Glu-Glu-Leu-Gly-Lys-Arg-Glu-Val-Thr-Ile-Pro-Pro-Lys-Tyr-Arg-Glu-Leu-Leu-Ala-NH2 | ||||||
| Shortening | Ac-DPMSSTYIEELGKREVTIPPKYRELLA-NH2 | ||||||
| Formula | C142H230N36O44S | ||||||
| Molar Mass | 3177.63 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
Acetyl-Calpastatin(184-210)(human)
CAS: 123714-50-1 F: C142H230N36O44S W: 3177.63
Acetyl-Calpastatin(184-210)(human) is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and
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