Bioactivity | Acepromazine-OTs is a cereblon (CRBN) ligand used in the recruitment of the cereblon (CRBN) protein. Acepromazine-OTs can be connected to the target protein ligand through a linker to form a PROTAC molecule, TrimTAC1 (HY-169355)[1]. |
CAS | 102951-20-2 |
Formula | C24H23NO4S2 |
Molar Mass | 453.57 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Panrui Lu, et al. Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders. Cell. 2024 Oct 30:S0092-8674(24)01197-8. |