| Bioactivity | Acanthoside B is a potential bioactive lignan with anti-inflammatory and anti-amnesic activities. Acanthoside B can be used for alzheimer's disease and lung inflammation research[1] |
| In Vivo | Acanthoside B (oral gavage; 10-20 mg/kg; 7 days prior to Scopolamine injection) attenuates Scopolamine inflicted AD-like amnesic traits by restoring the cholinergic activity, decreasing the endogenous antioxidant status, suppressing neuroinflammation, and activating the TrkB/CREB/BDNF pathway in mice[1]. Animal Model: |
| Name | Acanthoside B |
| CAS | 7374-79-0 |
| Formula | C28H36O13 |
| Molar Mass | 580.58 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Govindarajan Karthivashan, et al. Cognitive-enhancing and ameliorative effects of acanthoside B in a scopolamine-induced amnesic mouse model through regulation of oxidative/inflammatory/cholinergic systems and activation of the TrkB/CREB/BDNF pathway. Foo [2]. Ju Hee Lee, et al. Inhibition of Lung Inflammation by Acanthopanax divaricatus var. Albeofructus and Its Constituents. Biomol Ther (Seoul). 2016 Jan;24(1):67-74. |
Acanthoside B
CAS: 7374-79-0 F: C28H36O13 W: 580.58
Acanthoside B is a potential bioactive lignan with anti-inflammatory and anti-amnesic activities. Acanthoside B can be u
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