Bioactivity | Ac4ManNAz is an azido-containing metabolic glycoprotein labeling reagent. Ac4ManNAz can be used to selectively modify proteins. Ac4ManNAz can be used in cell labeling, tracking and proteomic analysis[1][2]. | |||||||||
Invitro | Ac4ManNAz (10 μM) shows the least effect on cellular systems and has a sufficient labeling efficiency for cell labeling, tracking and proteomic analysis[1].Ac4ManNAz (50 μM) leads to the reduction of major cellular functions, including energy generation capacity, cellular infiltration ability and channel activity[1]. | |||||||||
Name | Ac4ManNAz | |||||||||
CAS | 361154-30-5 | |||||||||
Formula | C16H22N4O10 | |||||||||
Molar Mass | 430.37 | |||||||||
Appearance | Solid | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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Reference | [1]. Han SS, et, al. Physiological Effects of Ac4ManNAz and Optimization of Metabolic Labeling for Cell Tracking. Theranostics. 2017 Mar 1;7(5):1164-1176. [2]. Han SS, et, al. Safety and Optimization of Metabolic Labeling of Endothelial Progenitor Cells for Tracking. Sci Rep. 2018 Sep 4;8(1):13212. |