| Bioactivity | Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes[1][2]. |
| Name | Ac-YVAD-pNA |
| CAS | 149231-66-3 |
| Sequence | Ac-Tyr-Val-Ala-Asp-{pNA} |
| Shortening | Ac-YVAD-{pNA} |
| Formula | C29H36N6O10 |
| Molar Mass | 628.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pereira NA, et al. Some commonly used caspase substrates and inhibitors lack the specificity required to monitor individual caspase activity. Biochem Biophys Res Commun. 2008 Dec 19;377(3):873-7. [2]. Xin W, Wang Q, et al. A new mechanism of inhibition of IL-1β secretion by celastrol through the NLRP3 inflammasome pathway. Eur J Pharmacol. 2017 Nov 5;814:240-247. |
Ac-YVAD-pNA
CAS: 149231-66-3 F: C29H36N6O10 W: 628.63
Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key
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