PeptideDB

Ac-YVAD-AFC

CAS: 219137-85-6 F: C33H36F3N5O10 W: 719.66

Ac-YVAD-AFC is the the fluorometric peptide substrate of caspase-1and caspase-4, with λ excitation of 400 nm and λ emi
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Bioactivity Ac-YVAD-AFC is the the fluorometric peptide substrate of caspase-1and caspase-4, with λ excitation of 400 nm and λ emission of 505 nm[1][2].
Name Ac-YVAD-AFC
CAS 219137-85-6
Shortening Ac-YVAD-{AFC}
Formula C33H36F3N5O10
Molar Mass 719.66
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Furuoka M, et al. TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells. J Cell Physiol. 2016 Dec;231(12):2761-7. [2]. Guo RF, et al. Protective effects of anti-C5a in sepsis-induced thymocyte apoptosis. J Clin Invest. 2000 Nov;106(10):1271-80.