Bioactivity | Ac-YVAD-AFC is the the fluorometric peptide substrate of caspase-1and caspase-4, with λ excitation of 400 nm and λ emission of 505 nm[1][2]. |
Name | Ac-YVAD-AFC |
CAS | 219137-85-6 |
Shortening | Ac-YVAD-{AFC} |
Formula | C33H36F3N5O10 |
Molar Mass | 719.66 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Furuoka M, et al. TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells. J Cell Physiol. 2016 Dec;231(12):2761-7. [2]. Guo RF, et al. Protective effects of anti-C5a in sepsis-induced thymocyte apoptosis. J Clin Invest. 2000 Nov;106(10):1271-80. |